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Title: 0941 - Designing a Bio-printable Bone Implant for Maxillofacial Regeneration

Authors:

Ahmed Abdelkarim (Presenter)
University of Hawaii

Ahmad Abd El-Azeem, National research center

Abstract:

Objectives: Establish an easy and inexpensive 3D workflow using open-source imaging and CAD/CAM software for patient-specific implantable scaffold 3D printing and applicable to the treatment of Maxillofacial defects.

Methods: After CBCT scanning, Manual segmentation of the defect was performed utilizing the corresponding DICOM images (Invesalius V3.1) followed by threshold segmentation of the skull bone. The 3D mesh models were exported as STL file then imported, edited, and prepared for printing in MeshMixer software. Then, the STL files are printed into patient specific scaffolds with Nano Hydroxy Appetite powder (30% by weight) with 65% porosity (Sigma-Aldrich Co. LLC) using poly lactic acid ultra pue filament on a FDM 3D printer.

Results: The segmented model reflected morphological features that were necessary to achieve closure of the cleft in a patient specific fashion. The 3D printer was capable of printing a solid form of the defect in the early printing trials. The small size of the defect caused no distortion to graft material during the printing process. Clinically, the mesh was easily applied although the brittleness was a disadvantage during screw fixation. No signs of inflammation or allergy.

Conclusions: Invesalius and MeshMixer software are open-source software, which are easy to use and could be used to generate a 3D patient-specific implantable scaffolds.

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None

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